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PF-04929113 Mesylate

CAS No. 1173111-67-5

PF-04929113 Mesylate( SNX-5422 Mesylate | PF04929113 Mesylate | SNX5422 Mesylate )

Catalog No. M10581 CAS No. 1173111-67-5

The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 92 Get Quote
5MG 146 Get Quote
10MG 273 Get Quote
25MG 396 Get Quote
50MG 583 Get Quote
100MG 833 Get Quote
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Biological Information

  • Product Name
    PF-04929113 Mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor.
  • Description
    The prodrug of PF-04928473 (SNX-2112), a potent, orally bioavailable HSP90 inhibitor; inhibits several signaling pathways and induces apoptosis in CRPC LNCaP tumors in vivo.Blood Cancer Phase 1 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SNX-5422 Mesylate | PF04929113 Mesylate | SNX5422 Mesylate
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP90|HER2
  • Research Area
    Cancer
  • Indication
    Blood cancer

Chemical Information

  • CAS Number
    1173111-67-5
  • Formula Weight
    617.6377
  • Molecular Formula
    C26H34F3N5O7S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C.CS(=O)(=O)O
  • Chemical Name
    Glycine, trans-4-[[2-(aminocarbonyl)-5-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]phenyl]amino]cyclohexyl ester, methanesulfonate (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lamoureux F, et al. Clin Cancer Res. 2011 Jul 15;17(14):4916. 2. Rajan A, et al. Clin Cancer Res. 2011 Nov 1;17(21):6831-9.
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